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(2020) 182:855871 e823

While this process is beneficial to tissue injury by quickly achieving hemostasis, alteration of the balance between blood coagulation and fibrinolysis in favor of coagulation may be an inappropriate response

Preclinical and clinical pharmacology studies have also implicated the glutamatergic system in these disorders through known and suspected drug mechanisms (5456)

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What We Still Dont Know There are still major gaps in what we know about TB-500 in humans, including long-term safety, effects of repeated use, and impact across different populations over time