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In support of this assumption, the N66A mutant does not migrate at the same size as cystinosin(7)-GFP (Supplemental Figure 2, A and B), even though the mutation slightly reduces the protein size (approximately 90 kDa)

I voted no primarily for low-quality evidence around efficacy, the poor characterization of the bulk drug substance and the fact that there are approved medical therapies for all the proposed uses, Todd Durham, a senior vice president at Foundation Fighting Blindness, said in Fridays meeting