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Yeah, I've heard Huberman talk about that

Il faut videmment responsabiliser galement le public qui na pas recourir un mdicament pour des raisons non mdicales

Nature (2001) 413:16571

The MT-II safety case-report literature includes systemic toxicity with rhabdomyolysis (Nelson 2012) [9] , renal infarction (Peters 2020) [10] , multiple priapism cases requiring urological intervention (Brun 2019, Habous 2021) [11] [12] , eruptive dysplastic nevi, at least four documented melanoma diagnoses temporally associated with use (Paurobally 2011, Hjuler 2014) [13] [14] , and a 2009 Norwegian Adverse Drug Reactions Report case of sepsis with lung abscess and gluteal abscess with Staphylococcus aureus bacteremia following self-injection

Other adherence studies suggest oral semaglutide can perform similarly to established oral therapies and, in some groups, may show better persistence than injectable semaglutide over 12 months (source)