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Epidermal melasma showed network with a brownish homogenous pigmentation on dermoscopy while mixed melasma showed showed few areas of enhancement by woods light and irregular pigment network superimposed by dark brown or bluish-black granules, globules and blotches on dermoscopy

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SUMOylation modification-mediated cell death

FTIR confirmed successful incorporation of HA and GSH within the hydrogen-bonded PVA matrix, while DSC analysis revealed reduced crystallinity and enhanced thermal stability