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Immune metabolites [13], such as serine [14], succinate [15], -ketoglutarate [16], L-carnitine (LC) [17] and fatty acids (FAs) [18], are capable to manipulate polarization by remodeling intracellular metabolism in macrophages

June 2025: The European Medicines Agencys (EMAs) safety committee concluded that NAION is a very rare potential side effect of semaglutide medicines, like Wegovy