Aceast metod inovatoare nu numai c faciliteaz aplicarea, dar ar putea mbunti i absorbia peptide n organism, oferind rezultate maxime
Polley MY, Leung SC, McShane LM, Gao D, Hugh JC, Mastropasqua MG, et al
Stomach acid denatures protein structures
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A useful comparison point is the acylation chemistry described for semaglutide by Lau and colleagues in the Journal of Medicinal Chemistry in 2015 [2], which introduced a C18 diacid linked through a spacer to achieve albumin binding on a GLP-1 scaffold