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Adverse Reactions (6.1).] Sitagliptin Add-on Therapy in Patients with Type 2 Diabetes Inadequately Controlled on the Combination of Metformin and Rosiglitazone A total of 278 patients with type 2 diabetes participated in a 54-week, randomized, double-blind, placebo-controlled study designed to assess the efficacy of sitagliptin in combination with metformin and rosiglitazone

And prebiotics, including oligosaccharides such as galactose oligosaccharides, barley foodstuff, fructooligosaccharides, and others, are metabolized by gut microorganisms to form SCFAs that influence the local microenvironment to preferentially favour growth of certain flora [158, 304]

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