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As the authors stated, To our knowledge this is the first lifestyle intervention study where remission of T2D has been studied with 100% remission with a feeding study using meals and food obtained from local grocery stores. However, unlike GLP-1 drugs, a calorie-restricted diet with the same macronutrient composition as the Zone diet causes weight loss without loss of lean body mass in both individuals with type 2 diabetes (7) as well as those with pre-diabetes (8)

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IGF-1 is also involved in insulin like growth, helping regulate how the body uses glucose and amino acids for energy and muscle building