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Category 2 Key clinical evidence Sermorelin FDA-era pediatric trials + PK data Tesamorelin Phase 3 visceral fat data CJC-1295 (DAC) Phase 1 PK and GH/IGF-1 duration data Typical research dose Sermorelin 200-300 mcg nightly Tesamorelin 2 mg daily CJC-1295 (DAC) 1-2 mg weekly Main use case Sermorelin GH optimization, sleep, recovery Tesamorelin Visceral fat / metabolic context CJC-1295 (DAC) Sustained GH/IGF-1 elevation All three target the same receptor but are not interchangeable

Mitochondrial vs Growth Hormone Axis Pathways Tesamorelins research relevance is entirely tied to the growth hormone axis it binds to GHRH receptors on the pituitary

Most peptides are administered via subcutaneous injection (a small injection just under the skin)

The Kuceki study builds on this by adding dutasteride and copper peptides and using a tattoo machine for more precise delivery