doi.org/10.4137/CMRH.S14681 Xu Y, Nisenblat V, Lu C, et al

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Heme oxygenase-1 protects human melanocytes from H2O2-induced oxidative stress via the Nrf2-ARE pathway
Thus, SSG does not simply suppress or promote apoptosis, but instead functions as a context-dependent redox rheostat that determines the threshold and direction of apoptotic signaling
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