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Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs

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Duration Protocols Common Adverse Reactions Growth hormone-related compounds may cause fluid accumulation, joint discomfort, or tingling sensations

Carbamazepine should be started at 100 mg up to twice daily, and titrated in steps of 100 200 mg every two weeks, until pain is relieved