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In particular, glutathione plays a major role in the redox process.86 Glutathione exerts various effects in the CNS including directly detoxifying drugs, ROS, and electrophilic xenobiotics

Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

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Eventually, the sequential activation of caspase 3 (CASP3), a principal executor of apoptosis, is induced by the activation of initiator CASP8 or CASP10 via cell death receptor pathways, and CASP9 via mitochondrial pathways