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These findings underscore the potential of natural adjuvants in thyroid therapy, particularly due to their multi-target effects (e.g., anti-inflammatory, immunomodulatory, and antioxidant) which align well with the complex pathophysiology of thyroid disorders

Changes in bowel habits that are severe or persistentsuch as bloody stools, black tarry stools, or diarrhoea lasting more than a few daysrequire medical evaluation to rule out other causes

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It is also useful in small bowel disease and in hepatobiliary and pancreatic disease