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Although NSAIDs have demonstrated efficacy in reducing neuroinflammation and improving BBB function, their use is limited by potential side effects, including gastrointestinal bleeding and cardiovascular risks (Kadueviius, 2021)

Most of these side effects are mild, but, medical evaluation is recommended to avoid serious side effects and should be treated under supervision

1 mM MgSO 4 , 120 M KH 2 PO 4 , 74 M Na 2 HPO 4 , 1 mM CaCl 2 , 500 M KCl, 15 mM NaCl, and 500 M NaHCO 3 in dH 2 O

Finasteride BNF

However, selenium should not be routinely supplemented in non-deficient individuals [55, 63], in particular because chronic excess may lead to toxicity (selenosis)