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AMPT exerts its inhibitory actions on tyrosine hydroxylase, which will lead to a severe impairment in the endogenous production of dopamine [25, 31]

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Absence of tissue inhibitor of metalloproteinase-4 (TIMP4) ameliorates high fat diet-induced obesity in mice due to defective lipid absorption

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Januvia and Janumet assist the pancreas by increasing incretin levels (specifically, GLP-1), by impairing the production of DPP-4, a protein which breaks down GLP-1