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Table 1 : Adverse Reactions Reported in 5% of Adults with Type 2 Diabetes Mellitus Treated with Empagliflozin added on to Metformin HCl plus Sulfonylurea and Greater than with Placebo in a 24-week Placebo Controlled Clinical Trial Empagliflozin Clinical Trials In Adults With Type 2 Diabetes Mellitus The data in Table 2 are derived from a pool of four 24-week placebo-controlled trials and 18-week data from a placebo-controlled trial with basal insulin in adult patients with type 2 diabetes mellitus

A pharmacological approach targeting many MetS components and extensive gene and miRNA Therapy management may be necessary for high-risk people

Thats pretty scary

10.1172/JCI31265 225 MarinoS

Safety is naturally one of the first questions anyone asks when considering a relatively new compound