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The half-life of 159 to 195 hours means there is some flexibility, a day early or late will not ruin the protocol, but regular weekly timing produces the most stable plasma levels

Theres also a similar class of medications called dual GLP-1 and GIP receptor agonists, and tirzepatide (the generic name for Mounjaro and Zepbound) is the only drug available in the U.S

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This is especially true if you are pregnant, nursing, or taking medications that affect blood pressure or the immune system