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In conclusion, GLP-1-based therapy emerges not merely as a promising option but as a currently available, evidence-supported pharmacological strategy for MC4R -deficient obesity in regions where these agents are accessible

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SIN mitigates myocardial ischemia reperfusion injury by inhibiting myocardial cell apoptosis, oxidative stress, and reducing calcium ion levels, further alleviating arrhythmias caused by ischemiareperfusion