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In another study, the role of MOTS-c in TGF-/Smad pathway-mediated osteogenesis was again validated by silencing TGF- and Smad and observing changes in the expression of downstream osteogenic genes ( 3.2.3 Role of MOTS-c in the synthesis of type I collagen by osteoblasts In addition, MOTS-c has been shown to promote the expression of type I collagen secreted by osteoblasts

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As an example, prostate cancer and diffuse large B-cell lymphoma, use FAO as the main source of energy and express FAO enzymes at high levels (Liu, 2006

Similarly, mounting evidence suggests that the immune response contributes to neuronal death as a cause rather than a consequence (22)