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This preparation was used in in vitro assays on human fecal slurry while monitoring the levels of TMA released over time, and it was also tested in vivo in both Mus musculus C57BL/6 (FMO3 +/+ ) strain WT and C57BL/6 -Fmo3em1Smoc (KO) mouse models to measure the trimethylamine N-oxide (TMAO) and TMA levels in the blood and urine, along with gut microbiota analysis in feces via next-generation sequencing (NGS)
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Therefore, only microsurgery, which works for medium and large-sized tumors, can result in a full cure
Martin Holst Lange, executive vice president, chief scientific officer and head of Research and Development, at Novo Nordisk
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