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By stabilizing drug bioavailability while reducing neutrophil activation, pro-inflammatory cytokine secretion, and osteoclast activity, the formulation minimizes gastrointestinal toxicity, offering superior efficacy in managing gout-related pain, joint destruction, and systemic complications compared to conventional oral therapies (Li Z

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Here, we discuss the increasing evidence for redox dysregulation as an important and primary contributor to ALS pathogenesis, which is associated with multiple disease mechanisms

While such approaches are promising, systematic immuno-safety assessment frameworks remain limited, and predictive models for patient-specific immune responses are urgently needed