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relevant for pre existing CVD

Diabetologia 65(12):19251966

However, Wegovy has shown slightly more effectiveness in terms of weight loss in some studies, with patients losing an average of 15% of their body weight over 68 weeks compared to 10% for Ozempic users

This approach lets you establish a baseline for bupropion side effects, confirm the antidepressant dose is correct, and ensure you tolerate the medication before adding the complexity of tirzepatide