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The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549

Real-World Data In a registry of 1,200 adults with type 2 diabetes and obesity, 65% reported 2% body weight reduction at six months, and 30% lost 5%

And Recent studies have indicated that GLP-1R signaling exerts protective effects against atherosclerosis and endothelial dysfunction, along with anti-inflammatory effects on macrophages and anti-proliferative effects on smooth muscle cells (36)