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4.2.4 Targeting necroptosis in CP-induced AKI Given the central role of the necroptotic pathway and its associated inflammation in the pathogenesis of CP-induced AKI along with their potential role in AKI-to-CKD transition, multiple agents with anti-necroptotic activity were tested in the CP-induced AKI model

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Ketone bodies are known to be generated from acetyl-CoA when a large amount of acyl-CoA remains unmetabolised following the TCA cycle

Computerized morphometric analysis of eryptosis