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111 have led to a series of well-characterized inhibitors

Two weeks before admission, she complained to her family of persistent dizziness and a foggy head, with appetite loss, for which she consulted her primary care physician

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Such changes could reduce the transamination activity, as suggested by an interference with the formation of diaminovalerate, a proposed metabolic intermediate in this catalytic reaction of GSAAT ( In light of experimental evidence showing the different monomeric and dimeric states of the Cys substitution mutants compared to GSAAT(WT), we propose that Cys168 and Cys190 are cruical for the protein activity and likely function as redox-active residues