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Limitations and clinical implications While initial preclinical findings suggest potential benefits, several important limitations must be considered

doi: 10.1128/aac.00343-16, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 466

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Formal human pharmacokinetic data on BPC-157 remain absent from published clinical literature as of 2026

Many of these compounds interact with immune pathways and peripheral systems, making it difficult to attribute observed effects solely to the modulation of angiogenesis within the CNS