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However, given their heart-protective effects, they may also be recommended for patients at high risk of cardiovascular disease, even if they do not have diabetes
Sitagliptin attenuates inflammatory responses in lipopolysaccharide-stimulated cardiomyocytes via nuclear factor-B pathway inhibition
This may explain why some patients would have higher risk of preeclampsia or hypertensive disorders in pregnancy, and may also explain why these patients were delivered by cesarean section. Lemas said the sample size for the study was small, and larger real-world studies involving multiple sites are needed
doi: 10.1089/ars.2007.1528 16 AveryJCHoffmannPR
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