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Shifting the circadian physiological clock of the body raises the chances of developing intestinal dysbiosis, which in return leads to inflammatory and metabolic diseases including cancer, diabetes and intestinal inflammatory diseases (Reynolds et al., 2017)

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36 If high enough suspicion of IEM, consider starting IV sodium benzoacetate/sodium phenylacetate (Ammonul) and L-arginine to help with nitrogen excretion

The fundamental drivers of this expansion are rooted in the molecule's versatility