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Many patients are on a combination of an SGLT2 inhibitor with a GLP-1 receptor agonist or tirzepatide (a dual agonist) and have incredible success without adverse reactions, but we are still figuring out the patient characteristics that would put them at higher risk of poor outcomes. Bagley is the senior editor of Endocrine News

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Furthermore, with the results of the isobologram and combination index analysis, the synergistic effects were also evaluated showing nystose and panose combinations having the greatest synergistic effects (114)