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Semaglutide Might Be Best If: You have a history of type 2 diabetes and need a medication with a proven track record

Benefits include reduced appetite, consistent weight loss, improved insulin sensitivity, and better control over metabolic health markers

[3] [4] These medications work by mimicking the incretin hormone glucagon-like peptide-1, which enhances insulin secretion, suppresses glucagon release, and significantly reduces appetite primarily through central satiety pathways, with some slowing of gastric emptying (an effect that may attenuate over time)

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Understanding Oral Semaglutide Side Effects Like all medications, oral semaglutide can cause side effects, ranging from mild to moderate