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Understanding steady state also explains a common frustration

Many patients using these medications have reported positive experiences, particularly regarding weight management

doi: 10.1152/ajpgi.00293.2015

A vial that looks perfectly clear and normal may have lost 20-30% of its active peptide through deamidation and hydrolysis without any visual indication

While sommarutide is undoubtedly an exciting potential treatment option, there is still a lack of clear clinical data on the mechanism of action of GLP-1 agonists in NASH, such as whether GLP-1 agonists have a direct, independent role in improving NASH, or simply by improving body weight, insulin resistance, and so on