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Emerging studies suggest that ferroptosis exacerbates PF progression by promoting macrophage polarization, fibroblast proliferation, and extracellular matrix deposition, ultimately leading to alveolar epithelial cell death and fibrotic tissue remodeling

Pinton P, Giorgi C, Siviero R, Zecchini E, Rizzuto R

High fructose consumption results in pathological changes such as insulin resistance, dyslipidemia, and hypertension in rats resembling metabolic syndrome

[2] [6] In healthy adults, vitamin B 12 deficiency is not common, mainly because body stores of the vitamin are substantial and turnover is slow, with relatively low dietary requirements