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Some EO ingredients, especially monoterpenes and phenylpropanoids (thymol, carvacrol, eugenol, and cinnamaldehyde), interact with hepatic drug-metabolizing enzymes and alter their activities, especially those in the livers cytochrome P450 family (CYP3A4, CYP2C9, and CYP2D6), as well as with the transporter P-glycoprotein [200]

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ADPN functions by enhancing FAO and ceramidase activity, reducing intracellular ceramide levels, and increasing sphingosine-1-phosphate concentrations

M., Cruzat, V

They havent been tested in people who are pregnant or actively trying to conceive