semaglutide versus tirzepatide side effects beat in the first head to head trial., 72 weeks: 20.2% of body weight lost vs 13.7%. Waist down about 18 cm vs 13 cm (DOI: 10.1056/NEJMoa2416394)., Why: semaglutide hits one Tirzepatide vs. Semaglutide for Weight

Provenzano M, Puchades MJ, Garofalo C, Jongs N, DMarco L, Andreucci M, De Nicola L, Gorriz JL, Heerspink HJL

The duration varies based on your starting dose, how quickly your dose increases, and your individual tolerance

Some users find the tablets difficult to swallow or report an unpleasant aftertaste

Read next Anna Medaris is a health correspondent at Insider with more than a dozen years of experience covering women's health, fitness and nutrition, sex and relationships, medical conditions, and psychology

Growth hormone tends to increase blood glucose through insulin antagonism and increased hepatic glucose production, an effect that can be problematic in some research contexts