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Pyroptosis and subsequent inflammasome activation were evaluated by cleaved gasdermin D, cleaved caspase-1, and NLRP3, IL-1 and IL-18 expression

Both medications require clinician assessment for safety, monitoring, and dose adjustments, and both are offered through telehealth programs that include lab testing and follow-up

CA extract and its bioactive rutin showed significant inhibitory activity against pancreatic lipase and alpha-amylase, but lower than orlistat, an anti-obesity drug