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The dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist tirzepatide improves cardiovascular risk biomarkers in patients with type 2 diabetes: A post hoc analysis

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When acting on the melanocortin 1 receptor (MC1R), melanotan stimulates melanin production and tyrosinase activity, leading to melanocyte proliferation and skin hyperpigmentation (Figure 3)

Gen Comp Endocrinol (1995) 97:1330

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