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The outcomes of these trials was largely positive, with the key findings being that treatment with AOD9604 was safer and better tolerated than supplementation with whole human growth hormone molecule

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Phase 1 is believed to correspond to the high level of activity in the primary afferent as by C-fiber activation due to peripheral stimulation, 9 whereas phase 2 seems to result from the continuous low level of small afferent input, together with a facilitated state of spinal processing