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In the following sections, we summarize some of the most important aspects of mGSH physiology, its role in mitochondrial function and release of mitochondrial apoptotic factors and the impact of its depletion in disease

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Low levels of glutathione can lead to increased oxidative stress and insulin resistance

Concomitant enzyme inducers: Isoniazid, rifampin, carbamazepine, phenytoin, phenobarbital increase oxidative metabolism