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Weight loss was accompanied by improvements in cardiometabolic parameters, including a decrease in systolic blood pressure (-9.9 mmHg) and waist circumference (-17.5 cm) (placebo-adjusted: 6.7 mmHg and 13.5 cm, respectively)

Core functional layers of ferroptosis The heterocyclic trioxirane compound [1,3,5-tris((oxiran-2-yl)methyl)-1,3,5-triazinane-2,4,6-trione (TGIC)], recognized for its anticancer properties, is used as the core scaffold to conjugate a non-steroidal anti-inflammatory drug, yielding the novel compound BY1 [131]

10.1038/s41598-020-61112-0 104 ValdecantosM