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Research indicates that insulin resistance increases slightly during the luteal phase due to progesterone, which may cause small blood sugar fluctuations in patients already managing diabetes or prediabetes

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Clarity here = better traction later

If someone is losing weight on a GLP-1 medication but also under-eating, losing strength, and unable to resistance train because of pain, that is not an optimized system

At one year, patients taking tirzepatide had a 38% lower rate of cardiovascular death or worsening heart failure compared to placebo