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Witte, Molecular mechanisms of cancer metastasis via the lymphatic versus the blood vessels
Presented at the 2026 ASCO Annual Meeting (Abstract 10506)
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The clinical consequence of this REDOX signature was significant, with REDOX high tumors exhibiting inferior objective response rates across two separate immunotherapy clinical trials- 39% vs 71% in one, and 17% vs 38% in the other, with corresponding worse progression free and overall survival as a result [76]
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