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Acknowledgments BD and MV are founded by the Center Scientifique de Monaco (CSM) and the Monegasque association GEMLUC (Groupement des Entreprises Mongasques dans la Lutte contre le Cancer)

Recent studies have highlighted the significance of FPN in regulating ferroptosis

Matsui and Williams, 2010)

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HEK293 cells stably expressing of the reporter protein FIXgla-Fas or FIXgla- Met .Luc ( Metridia luciferase) were obtained by transfecting of HEK293 cells with corresponding chimeric reporter protein constructs in pcDNA3.1 plasmid DNA using Xfect transfection reagent, according to the manufacturers instruction