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Interested in starting a GLP-1 program at your clinic or practice

MT-1 (Melanotan 1, also called afamelanotide) is a synthetic 13-amino-acid analog of alpha-melanocyte-stimulating hormone (alpha-MSH) that selectively activates melanocortin-1 (MC1R) and to a lesser extent MC4R receptors

ACC guidelines published in 2024 for lower extremity arterial disease management do not discuss GLP-1 RA as part of management, likely due to the recency of the STRIDE trial findings [45]

However, some people find that its side effects are worse and may prefer a different medication

Nardinia M, Finkelstein EI, Reddy S, Valacchi G, Traber M, Cross CE, et al