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recruited 281 participants with T2DM living with overweight or obesity who were randomized to receive once-weekly injections of placebo, 1.5 mg of GLP-1RA dulaglutide, or tri-agonist retatrutide maintenance doses of 0.5 mg, 4 mg (starting dose 2 mg), 4 mg (no escalation), 8 mg (starting dose 2 mg), 8 mg (starting dose 4 mg), or 12 mg (starting dose 2 mg)
Phorbol ester responsiveness of the glutathione S-transferase P1 gene promoter involves an inducible c-jun binding in human K562 leukemia cells
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New technologies are being harnessed to enhance trial design, streamline patient identification and optimize recruitment efforts, critical factors in rare disease studies
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