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Supplementary Results Description 1 provides explanations regarding participants cardiovascular risk factors, anthropometric parameters and quality of life throughout the trial

After substantial weight reduction, loose skin can appear over the abdomen, arms, thighs, breasts or under the chin

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Finally, we thank our funding sources: Genome Canada and Genome BC (275SIL and 298SGC), Canadian Institutes of Health Research (GP1-155868), BC Childrens Hospital Research Institute and BC Childrens Hospital Foundation, Illumina (in-kind), Provincial Health Services Authority, Alberta Children's Hospital Foundation and Canadian Rare Diseases: Models & Mechanisms Network (RDMM)