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MZB cells also rely disproportionately on lipid metabolism when compared to FoB cells, suggesting that lipid metabolism is important for natural antibody production 142

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Allergy risk to cobalt or preservatives (rare) Energy improvement: 24-72 hours Reticulocyte response: 3-5 days Neurological improvement: Weeks to months Hematological normalization: 4-8 weeks Maximum nerve repair: Up to 1 year Injection site reactions (15-20%) Mild diarrhea (initial doses) Itching/eczema (cobalt sensitivity) Transient anxiety (overstimulation) Headache (usually resolves quickly) Serious reactions are extremely rare

M.RosenzweigA.et al (2010)

The stains used for chromoendoscopy are transient, unlike the stains used to tattoo lesions, and the equipment needed for chromoendoscopy is widely available