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The sciatic nerve is identified and isolated 2 or 3 cm long and attached by a silk thread about 3 cm from the gastrocnemius

2008;10(3):547-557.[DOI] 27

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PAGln induces hypercontractility and altered Ca 2+ handling in cardiomyocytes The above physiological responses suggest that despite the lack of cardiac dysfunction as measured by echocardiography, there is a central effect of PAGln on the ability of the myocardium to contract and relax properly, manifesting as an elevation in LVEDP despite no change in afterload