Center for Digestive and Liver Diseases, Nara City Hospital, Nara, Japan Sapienza University of Rome, Unit of Rheumatology, Rome, Italy Enrico Arosio, MD, Sergio De Marchi, MD and others
These inconsistencies have prompted some investigators to explore the reliability of glutathione level measurements in blood as an indicator of oxidative stress-associated brain changes
F., Kim, M
In the present study, a mouse model of chronic oxidative stress due to compromised de novo GSH synthesis (GCLM KO) 16 exhibited unexpected protection from chronic alcohol consumption-induced hepatotoxicity and steatosis
While the largest percentage of intracellular iron is tightly bound to or incorporated into proteins as a cofactor or for storage, small portion of intracellular iron resides in the cytosol and intracellular organelles (e.g., lysosomes) and constitutes a redox-active liable iron pool, which regulates programmed cell death including ferroptosis 42