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doi: 10.1002/art.21975 29 RuthJHParkCCAminMALeschCMarotteHShahraraSet al
Type 1 DM Pathophysiology: An autoimmune T-cellmediated destruction of pancreatic beta cells results in absolute insulin deficiency
26 KumarA.ZhangK
In the context of wet age-related macular degeneration (AMD), geniposide (GEN), a GLP-1RA, is found to downregulate HB-EGF (heparin-binding epidermal growth factor) secretion from retinal pigment epithelium (RPE) cells under hypoxic conditions through the miR-145-5p/NF-B signaling axis
Because it is a dual agonist, it is hitting more receptors, which for sensitive individuals might mean more complexity in how they feel
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