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This article summarizes the development of the DPP-4 inhibition concept from its early stages in the 1990s

The major source of ROS comes from non-enzymatic processes in the mitochondrial respiratory chain ( Everything has two sides, and it is crucial for cell to regulate ROS levels to avoid oxidative stress

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Here, we review the current knowledge on the role of estrogens and estrogen-like molecules in the neuro/gliogenic processes and the regulation of neuronal survival and neurodegeneration

10.1136/bmjopen-2013-004365 25 MasarwaR.LevineH.GorelikE.ReifS.PerlmanA.MatokI